Functional redundancy in mitotic force generation.
نویسندگان
چکیده
منابع مشابه
Functional redundancy in mitotic force generation
HE pushing and pulling forces that characterize the rocess of mitosis have fascinated and frustrated biolo-ists for over a century. While considerable progress has been made in understanding how these forces are used in mitosis, the nature of the molecules that generate the forces has remained obscure., have demonstrated that members of the kinesin su-perfamily of microtubule motors are likely ...
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The mitotic spindle assembles to a steady-state length at metaphase through the integrated action of molecular mechanisms that generate and respond to mechanical forces. While molecular mechanisms that produce force have been described, our understanding of how they integrate with each other, and with the assembly/disassembly mechanisms that regulate length, is poor. We review current understan...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1993
ISSN: 0021-9525,1540-8140
DOI: 10.1083/jcb.120.1.1